What is HPV?

Overview of Human Papillomavirus

The human papillomavirus (HPV) is a sexually transmitted infection that spreads through direct contact. Approximately 150 different types of HPV have been identified. Between 2012 and 2016, around 34,800 cancers related to HPV were reported annually in the United States. HPV can lead to warts on the genital area, respiratory tract, and even on the hands and feet. It is estimated that most sexually active individuals will contract HPV at some point. While many HPV infections resolve spontaneously, some can progress to warts or cancer. Regular medical check-ups can significantly reduce the risk of developing cancer associated with certain HPV infections.

HPV-Related Cancers

Several types of cancers can develop years after an HPV infection, including vulvar, penile, cervical, and oropharyngeal cancers (affecting the back of the throat). Fortunately, various screening and prevention strategies, including a vaccine for HPV, are available.

HPV Screening

Cervical Cancer Screening for Women

Women are advised to have regular cervical cancer screenings through annual Pap smears. This procedure collects cervical cells to check for abnormalities that may indicate cancer. An HPV test, which looks for the DNA of cancer-causing HPV, may also be conducted during this examination. In Canada, HPV DNA testing is accessible, although it may not be covered by provincial health insurance. Currently, research is underway regarding HPV testing for men. Abnormal results from these tests do not automatically confirm a cervical cancer diagnosis; further evaluation is necessary based on the findings. If cervical cancer is diagnosed, an oncology healthcare team will develop a treatment plan.

HPV Vaccine

Types and Availability of HPV Vaccines

Three HPV vaccines are approved for use in Canada and the United States. The most commonly used vaccines in North America are Gardasil (4-valent) and Gardasil-9 (9-valent), while Cervarix (bivalent) is available in Canada. Gardasil protects against four types of HPV that are most likely to cause cancer and genital warts, while Gardasil-9 offers additional protection against five other cancer-causing types. Both Gardasil vaccines are suitable for men and women, whereas Cervarix is approved only for women.

Vaccination Recommendations

In Canada, the vaccines are recommended for women aged 9 to 45 and men aged 9 to 26, typically requiring three doses. In the United States, vaccination is advised for individuals aged 9 to 26. Although adults over 26 can receive the vaccine, they are more likely to have already been exposed to HPV. It is important to note that even if someone has been exposed to the virus or is vaccinated, the risk of HPV infection can increase with each new sexual partner. Therefore, consulting with a healthcare provider about the benefits of HPV vaccination is advisable. The vaccines are safe, have undergone rigorous testing, and do not cause HPV infections or exacerbate existing infections.

Conclusion

There are effective measures to protect against human papillomavirus and related cancers. While the available vaccines are effective against specific types of HPV, they do not provide complete protection against all cancer-causing strains. Therefore, routine screening and practicing safe sex are essential. It is recommended to consult with a healthcare provider for personalized guidance on HPV prevention and vaccination options.